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Medchemexpress LLC EX229, a benzimidazole derivative | 1219739-36-2 | MFCD31696597 | 99.4% | 431.87 | C24H18ClN3O3 | 5 MG
SDP

Supplier:  Medchemexpress LLC HY1127695MG

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EX229 is a benzimidazole-derived small-molecule allosteric activator of AMP-activated protein kinase (AMPK) used for biochemical and cellular research. It binds AMPK complexes with submicromolar affinity and shows potent cellular activity, suitable for pathway and metabolic studies.

  • Potent allosteric activator of AMPK (Kd ≈ 0.06 μM for primary complexes).
  • Demonstrated cellular activity (EC50 ≈ 3 nM in Sf21 cell assay).
  • High purity (≈99.4%).
  • Soluble in DMSO (~13 mg/mL) with recommended in vivo formulation protocols.
  • Stable as powder and in solvent when stored under recommended conditions.
  • Available in small-mass packs and DMSO solutions for screening workflows.

Catalog No. 50-187-2425


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