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Eurofins Discoverx cAMP Hunter eXpress CCR7 CHO-K1 GPCR Assay, 10-Plate Kit. (95-0070E2CP2L)
Supplier: Eurofins Discoverx 950070E2CP2L
The cAMP Hunter CCR7 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. CCL19) based activation of CCR7 GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type CCR7, a naturally Gi/Go coupled GPCR. Upon activation of CCR7, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
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