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Eurofins Discoverx PathHunter eXpress HRH4 U2OS β-Arrestin GPCR Assay, 10-Plate Kit. (93-0209E3CP0L)
Supplier: Eurofins Discoverx 930209E3CP0L
The PathHunter HRH4 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. histamine) based activation of HRH4 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged HRH4 and EA-tagged β-Arrestin-2. Activation of HRH4 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
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