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Eurofins Discoverx PathHunter eXpress MRGPRF CHO-K1 β-Arrestin Orphan GPCR Assay, 10-Plate Kit. (93-0433E2ACP2L)
Supplier: Eurofins Discoverx 930433E2ACP2L
The PathHunter MRGPRF eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of MRGPRF GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged MRGPRF and EA-tagged β-Arrestin-2. Activation of MRGPRF stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
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