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Eurofins Discoverx PathHunter eXpress rTrkA-rP75 Functional Assay, 10-Plate Kit. (93-1014E3CP16L)

Catalog No. 502001842
Encompass

The PathHunter eXpress rTrkA-rP75 Functional Assay provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting RTKs. This kit assesses RTK activation via detection of activated rTrkA and rP75 dimerization-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses ProLink-tagged rTrkA and an EA-tagged SH2 domain protein. It also overexpresses an untagged coreceptor, rP75 Upon ligand-induced receptor activation, SH2-EA recruitment leads to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Rat version of the protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.

Catalog No. 50-200-1842 Supplier Eurofins Discoverx Supplier No. 931014E3CP16L
May include imposed supplier surcharges.
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The PathHunter eXpress rTrkA-rP75 Functional Assay provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting RTKs. This kit assesses RTK activation via detection of activated rTrkA and rP75 dimerization-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses ProLink-tagged rTrkA and an EA-tagged SH2 domain protein. It also overexpresses an untagged coreceptor, rP75 Upon ligand-induced receptor activation, SH2-EA recruitment leads to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Rat version of the protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.

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