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Eurofins Discoverx InCELL Hunter eXpress SIK1 Kinase Binding Assay, 10pl Kit. (96-0051E15CP0L)
Supplier: Eurofins Discoverx 960051E15CP0L
The InCELL Hunter eXpress SIK1 Kinase Binding Assay provides an easy-to-use cell based assay to study small molecule drug candidates that engage with kinases. This kit assesses compound-engagement-based stabilization of SIK1 via detection of SIK1 levels. This product uses EFC technology. The cell line included overexpresses SIK1 target protein fused to ProLabel. In the absence of compound that binds and stabilizes the target, this protein is degraded and no EFC signal is produced. When compound engages and stabilizes the target, EA contained in the detection reagent produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
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