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Cayman Chemical EZ-EndoxIfen 10mg

Supplier: Cayman Chemical 2150210 MG

A potent ATP-uncompetitive inhibitor of MEK1 (Ki 0 13 nM in the presence of ATP) inhibits the proliferation of A375 BRAF(V600E) and HCT116 KRAS(G13D)-mutant cancer cell lines (EC50 7 and 42 nM respectively) upregulates pro-apoptotic BIM
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