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Apexbio Technology LLC EZ Cap Human PTEN mRNA (ψUTP) 5x1mg (1mg/mL)
Supplier: Apexbio Technology LLC R10265
PTEN mRNA encodes a a tumor suppressor gene (Phosphatase and Tensin homolog deleted on chromosome 10) that antagonizes the activity of PI3K a key enzyme involved in anti-apoptotic and pro-tumorigenic Akt activation EZ Cap Human PTEN mRNA ( UTP) is provided at 1 mg/mL This mRNA is synthesized through co-transcriptional capping resulting in a Cap 1 structure The incorporation of UTP and addition of poly(A) tail significantly enhances mRNA stability and lifetime both in vitro and in vivo Furthermore the poly(A) tail significantly contributes to improving the efficiency of translation initiation
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