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Apexbio Technology LLC EZ Cap Mouse CD80 mRNA (m1Ψ HA tag) 1mg (1mg/mL)
Supplier: Apexbio Technology LLC R10791
Mouse CD80 mRNA encodes CD80P Binding to CD28 and CTLA-4 receptors on T cells CD80 modulates T-cell activation and inhibition CD80 interacting with CD28 promotes T-cell activation and proliferation enhancing immune responses Its binding to CTLA-4 provides inhibitory signals maintaining immune tolerance and preventing excessive immune reactions CD80 have emerged as therapeutic targets in various immunotherapies such as treatments for autoimmune diseases transplantation rejection and cancer immunotherapy EZ Cap Mouse CD80 mRNA (m1 HA tag) is provided at 1 mg/mL and expresses mouse CD86 cytokine fused with an HA tag facilitating subsequent detection It contains a cap 1 structure generated via co-transcriptional capping Incorporation of modified nucleotides m1 along with a poly (A) tail minimizes RNA-induced innate immune activation and enhances mRNA stability and lifespan both in vitro and in vivo
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