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Apexbio Technology LLC EZ Cap Mouse GM-CSF mRNA (m1Ψ) 100ug (1mg/mL)
Supplier: Apexbio Technology LLC R10800.1
GM-CSF mRNA encodes Granulocyte-Macrophage Colony-Stimulating Factor (CSF) produced by T cells macrophages endothelial cells and fibroblasts It stimulates the differentiation of hematopoietic stem cells in bone marrow into granulocytes and macrophages thereby enhancing the body s immune response capability GM-CSF not only promotes leukocyte production but also enhances their functions such as improving phagocytosis and antigen presentation abilities Clinically GM-CSF is used to treat certain types of leukopenia and serves as an adjuvant in cancer immunotherapy EZ Cap Mouse GM-CSF mRNA (m1 ) is provided at 1 mg/mL It expresses mouse-derived GM-CSF cytokine It contains a cap 1 structure generated via co-transcriptional capping Incorporation of modified nucleotides m1 along with a poly (A) tail minimizes RNA-induced innate immune activation and enhances mRNA stability and lifespan both in vitro and in vivo
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