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Apexbio Technology LLC EZ Cap Mouse IL-12 mRNA (m1Ψ HA tag) 100ug (1mg/mL)
Supplier: Apexbio Technology LLC R10590.1
Mouse IL-12 mRNA encodes a cytokine Interleukin-12 secreted by antigen-presenting cells such as dendritic cells macrophages and B cells It promotes the activation and proliferation of T cells and natural killer (NK) cells thus enhancing the body s immune response IL-12 induces the differentiation of T cells into Th1 cells thereby enhancing cell-mediated immunity and increasing the production of interferon- (IFN- ) crucial for antiviral and antitumor immune responses EZ Cap Mouse IL-12 mRNA (m1 HA tag) is provided at 1 mg/mL encoding mouse IL-12 cytokine fused with an HA tag enabling convenient downstream detection of expressed proteins It contains a cap 1 structure generated through co-transcriptional capping Incorporation of modified nucleotides m1 along with a poly (A) tail minimizes RNA-induced innate immune activation and enhances mRNA stability and lifespan both in vitro and in vivo
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