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Apexbio Technology LLC EZ Cap Mouse IL-23 mRNA (m1Ψ HA tag) 1mg (1mg/mL)
Supplier: Apexbio Technology LLC R10671
Mouse IL-23 mRNA (Interleukin-23) encodes IL-12 cytokine It consists of two subunits IL-23 p19 and IL-12 p40 IL-23 binds to its specific receptor IL-23R activating downstream signaling pathways including the JAK-STAT pathway thus promoting inflammatory responses IL-23 is a potential therapeutic target for various diseases including psoriasis Crohn s disease and multiple sclerosis In recent years biological agents targeting IL-23 such as monoclonal antibodies have been developed for clinical application showing good efficacy and safety EZ Cap Mouse IL-23 mRNA (m1 HA tag) is provided at 1 mg/mL encoding mouse IL-23 cytokine fused with an HA tag enabling convenient downstream detection of expressed proteins With cap 1 structure generated through co-transcriptional capping incorporation of modified nucleotides m1 along with a poly (A) tail minimizes RNA-induced innate immune activation and enhances mRNA stability and lifespan both in vitro and in vivo
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