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Apexbio Technology LLC EZ Cap Mouse IL-23α mRNA (m1Ψ HA tag) 100ug (1mg/mL)
Supplier: Apexbio Technology LLC R10680.1
Mouse IL-23 mRNA encodes a subunit of interleukin-23 (IL-23) IL-23 has two subunits p19 (IL-23 ) and p40 IL-23 binds p40 to form a functional cytokine promoting differentiation and maintenance of Th17 cells which are essential in anti-microbial defense and autoimmune diseases Dysregulated expression of IL-23 is associated with multiple inflammatory diseases such as psoriasis Crohn s disease and multiple sclerosis IL-23 and its subunit IL-23 are therapeutic targets for these diseases and numerous biologics have been developed to inhibit their activity EZ Cap Mouse IL-23 mRNA (m1 HA tag) is provided at 1 mg/mL encoding mouse IL-23 cytokine fused with an HA tag enabling convenient downstream detection of expressed proteins With cap 1 structure generated through co-transcriptional capping incorporation of modified nucleotides m1 along with a poly (A) tail minimizes RNA-induced innate immune activation and enhances mRNA stability and lifespan both in vitro and in vi
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