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Apexbio Technology LLC EZ Cap Mouse IFN-γ mRNA (5mCTP ψUTP) 5x1mg (1mg/mL)
Supplier: Apexbio Technology LLC R10495
Mouse Interferon gamma mRNA encodes murine cytokine IFN- primarily secreted by activated T lymphocytes and natural killer (NK) cells It plays a critical role in the immune system including activation of macrophages to enhance their phagocytic and pathogen-killing capabilities IFN- promotes the function of antigen-presenting cells by increasing the expression of major histocompatibility complex (MHC) molecules thus enhancing antigen recognition by T cells As a result it performs a vital role in antiviral and anti-tumor immunity IFN- also regulates the Th1-type immune response while suppressing the Th2-type response maintaining immune balance EZ Cap Mouse IFN- mRNA (5mCTP UTP) is provided at 1 mg/mL It contains a cap 1 structure generated through co-transcriptional capping Incorporation of modified nucleotides 5mCTP and UTP along with a poly (A) tail minimizes RNA-induced innate immune activation and enhances mRNA stability and lifespan both in vitro and in vivo
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