Nuc-mScarlet mRNA encodes a fusion protein combining a nuclear localization signal (Nucleus-targeting signal) with the fluorescent protein mScarlet By fusing mScarlet with a nuclear localization signal it enables the monitoring of dynamic processes inside the nucleus in living cells in real-time Nuc-mScarlet exhibits high photostability and brightness making it particularly suitable for long-term imaging experiments Moreover the spectral properties of mScarlet are compatible with other fluorescent proteins such as GFP facilitating multiplex labeling experiments EZ Cap Nuc-mScarlet Probe mRNA (m1 ) is provided at 1 mg/mL specifically designed for nuclear-targeted expression of red fluorescent protein labels This mRNA is synthesized through co-transcriptional capping resulting in a Cap 1 structure The incorporation of m1 modifications poly(A) tail significantly enhances mRNA stability and lifetime both in vitro and in vivo