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Medchemexpress LLC EZM0414 | 2411748-50-8 | 99.1% | C22H29FN4O2 | 50 MG
SDP

Catalog No. 5000354853
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EZM0414 is a potent, selective, and orally bioavailable inhibitor of SETD2. It is used for the research of relapsed or refractory multiple myeloma and diffuse large B-cell lymphoma.

  • Potent, selective, orally bioavailable inhibitor of SETD2
  • IC50 of 18 nM in SETD2 biochemical assay
  • IC50 of 34 nM in cellular assay
  • Inhibits proliferation of MM and DLBCL cell lines
  • Well-tolerated and inhibits tumor growth in xenograft models
  • Almost 100% oral bioavailability in rats and mice

Catalog No. 50-003-54853 Supplier Medchemexpress LLC Supplier No. HY14485850MG
May include imposed supplier surcharges.
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EZM0414 is a potent, selective, and orally bioavailable inhibitor of SETD2. It is used for the research of relapsed or refractory multiple myeloma and diffuse large B-cell lymphoma.

  • Potent, selective, orally bioavailable inhibitor of SETD2
  • IC50 of 18 nM in SETD2 biochemical assay
  • IC50 of 34 nM in cellular assay
  • Inhibits proliferation of MM and DLBCL cell lines
  • Well-tolerated and inhibits tumor growth in xenograft models
  • Almost 100% oral bioavailability in rats and mice

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