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Medchemexpress LLC F 13714 fumarate | 208109-39-1 | 99.1% | 10 MG
Supplier: Medchemexpress LLC HY12890110MG
F 13714 fumarate is a selective 5-HT1A receptor biased agonist that exhibits antidepressant-like properties after a single administration in the mouse model of chronic mild stress.
- Selective 5-HT1A receptor biased agonist.
- Shows antidepressant-like properties after a single administration in the mouse model of chronic mild stress.
- Targets 5-HT1A autoreceptors.
- Normalizes depressive-like behavior in the forced swim test (FST) in UCMS mice.
- Rescues cortical and hippocampal deficits in p-ERK1/2 levels.
- Decreases immobility in mice.
- Decreases rectal body temperature in mice.
- Possesses antidepressant- and anxiolytic-like properties in naive rats.
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