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Cayman Chemical FA asy FluorometrIc Detect 1ea
SDP

Supplier:  Cayman Chemical 7003141 EA

Encompass_Preferred

An MC4R antagonist (Ki 3.16 nM) selective for MC4R over MC1R MC3R and MC5R (Kis 108 54.4 and 694 nM respectively) inhibits a-MSH-induced cAMP accumulation induced by in COS-1 cells expressing MC4R in a concentration-dependent manner increases food intake in free-feeding rats at 1 or 3 nmol/animal i.c.v increases the latency to tail withdrawal in the tail-flick test as well as inhibits morphine withdrawal-induced decreases in the latency to tail withdrawal in the tail-flick test in rats at 0.008 ng/animal i.c.v. reduces immobility time in the forced swim test as well as increases time in the open area and reduces the number of droppings in an open field test in rats at 100 UG/animal

Catalog No. 50-289-2723


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