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GENOVIS INC FABRICATOR IGG PROTEASE, 5000U
Supplier: GENOVIS INC A0FR1050
Detailed Information aEFabRICaTOR digests IgG only at one specific site just below the hinge region, resulting in F(ab')2and Fc-fragments. Since FabRICaTOR only cleaves at one specific site below the hinge region, there is no risk of over digestion if the incubation time is increased for several hours. FabRICaTOR digests IgG under physiological reaction conditions thus preserving the immunoreactivity. Best activity is obtained at 37a Deg. C but digestion can also be performed at room temperature using prolonged reaction time. SpeciesFabRICaTOR digests all subclasses of human, monkey, rabbit and sheep IgG. FabRICaTOR has limited activity on mouse IgG2a and IgG3 and for digestion of mouse IgG2a and IgG3 the use of FabRICaTOR Z is recommended.Follow this link to view a protease IgG digestion chart with species StabilityThe enzyme is reconstituted by addition of water and after reconstitution FabRICaT
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