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Medchemexpress LLC Fadrozole hydrochloride | 102676-31-3 | 99.9% | C14H14ClN3 | 1 ML
Supplier: Medchemexpress LLC HY1424710MM/1ML
Fadrozole hydrochloride (CGS 16949A) is a potent, selective, and nonsteroidal aromatase inhibitor that effectively inhibits estrogen production. It is intended for research use only and not for patient use.
- Potent and selective aromatase inhibitor with an IC50 of 6.4 nM.
- Inhibits estrogen production in hamster ovarian slices with an IC50 of 0.03 μM.
- Can suppress the synthesis of other cytochrome P-450 dependent steroids at higher doses.
- Prevents the development of spontaneous mammary neoplasms in female rats.
- Slows the development of pituitary pars distalis adenomas.
- Reduces the incidence of spontaneous hepatocellular tumors.
- Reduces parasite burden in male and female mice by 70%.
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