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Medchemexpress LLC Fadrozole hydrochloride | 102676-31-3 | 99.9% | C14H14ClN3 | 25 MG
Supplier: Medchemexpress LLC 25MGHY14247
Fadrozole hydrochloride (CGS 16949A) is a potent, selective, and nonsteroidal inhibitor of aromatase with an IC50 of 6.4 nM. It inhibits estrogen production in hamster ovarian slices and has various in vivo effects, including the prevention of certain tumors and reduction of parasite burden.
- Potent, selective, and nonsteroidal inhibitor of aromatase with an IC50 of 6.4 nM.
- Inhibits estrogen production with an IC50 of 0.03 μM.
- Inhibits progesterone production with an IC50 of 120 μM.
- Inhibits aromatase-mediated uterine hypertrophy in immature female rats with an oral ED50 of 0.03 mg/kg.
- Prevents development of benign and malignant spontaneous mammary neoplasms.
- Slows spontaneous development of pituitary pars distalis adenomas.
- Reduces incidence of spontaneous hepatocellular tumors.
- Reduces parasite burden in male and female mice by 70%.
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