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Bachem 5-FAM-LL-37 Trifluoroacetate
SDP

Supplier:  Bachem 4104169.0500

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5-FAM-LL-37 Trifluoroacetate, Fluorescein-5-carbonyl-Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser-OH, 2243219-81-8, C226H350N60O59, Mr 4851.63, 0.5mg. FAM-labeled (ab/em = 494/518nm) LL-37. LL-37 is an antimicrobial peptide with angiogenic activity. It corresponds to the C-terminal sequence (134-170) of the human cathelicidin antimicrobial protein hCAP18/LL-37. hCAP18/LL-37 is an effector of the innate immune system and is expressed in leukocytes and epithelial cells where it is upregulated in association with inflammation and injury. An overexpression of hCAP18/LL-37 in a series of breast carcinomas could be demonstrated. LL-37 has been suggested to stimulate epithelial cell proliferation partially through formyl peptide receptor-like 1 (FPRL1).

Catalog No. 50-194-6668


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