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Apexbio Technology LLC Famciclovir 104227-87-4 50mg
Supplier: Apexbio Technology LLC B194250
Famciclovir (104227-87-4) is an orally available small-molecule prodrug of penciclovir targeting viral DNA polymerase It is designed to enhance the bioavailability of penciclovir thereby improving inhibition of herpesvirus replication Famciclovir exerts its biological activity primarily through selective inhibition of herpes simplex virus (HSV) DNA polymerase by penciclovir which competes with natural nucleotides In cell-based assays famciclovir-generated penciclovir demonstrates potent antiviral activity with reported IC50 values ranging from 0 1 to 0 8 g/mL Based on these pharmacological properties famciclovir holds research potential in studies of HSV and varicella-zoster virus (VZV) infections
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