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Medchemexpress LLC Fargesin | 31008-19-2 | 370.40 | 20 MG

Supplier: Medchemexpress LLC HYN071920MG
Fargesin is a bioactive neolignan isolated from magnolia plants. It exhibits antihypertensive and anti-inflammatory effects. It is intended for research use only and not for sale to patients.
- Demonstrates antihypertensive effects in 2K1C hypertensive rats by attenuating oxidative stress and promoting NO release.
- Exhibits anti-inflammatory effects on THP-1 cells by suppressing the PKC pathway, including downstream JNK, nuclear factors AP-1, and NF-κB. Also shows anti-inflammatory effects on chemically induced inflammatory bowel disease in mice.
- Protects the hearts against ischemia/reperfusion injury in rats by attenuating oxidative stress and apoptosis, acting as a potential β₁ adrenergic receptor antagonist.
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