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  6. Fasentin, Tocris Bioscience™

Fasentin, Tocris Bioscience™

Catalog No. 610010
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10 mg
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Catalog No. Quantity
61-001-0 10 mg
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Catalog No. 61-001-0 Supplier R&D Systems Supplier No. 6100/10
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Description

GLUT1/GLUT4 inhibitor; also Fas-sensitizer

GLUT1 and GLUT4 inhibitor (IC50 = 68 μM). Preferentially inhibits GLUT4 over GLUT1. Sensitizes Fas receptor in a range of tumor cell lines (IC50 = 20 μM) by modulating the extrinsic apoptotic pathway downstream of TNF receptors but upstream of effector caspases.

Chemical Identifiers

CAS 392721-37-8
Molecular Formula C11H9ClF3NO2
Molecular Weight (g/mol) 279.64
MDL Number MFCD01001285
InChI Key GNYIJZMBLZXJEJ-UHFFFAOYSA-N
Synonym Fasentin
PubChem CID 879520
IUPAC Name N-[4-chloro-3-(trifluoromethyl)phenyl]-3-oxobutanamide
SMILES CC(=O)CC(=O)NC1=CC(=C(Cl)C=C1)C(F)(F)F

Specifications

Linear Formula C11H9ClF3NO2
Quantity 10 mg
Solubility Information Soluble to 100mM in DMSO and to 100mM in ethanol
Formula Weight 279.64
Percent Purity >98%
Physical Form Solid
Chemical Name or Material N-(4-Chloro-3-(trifluoromethyl)phenyl)-3-oxobutanamide

Safety and Handling

Recommended Storage Store at −20°C
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