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Medchemexpress LLC Fatostatin hydrobromide | 298197-04-3 | MFCD00760867 | 99.52% | C18H19BrN2S | 25 MG
Supplier: Medchemexpress LLC 25MGHY14452A
Fatostatin hydrobromide (125B11 hydrobromide) is a specific inhibitor of SREBP activation. It impairs the activation of SREBP-1 and SREBP-2 by binding to SCAP (SREBP cleavage-activating protein), which inhibits the ER-Golgi translocation of SREBPs. This action leads to a decrease in the transcription of lipogenic genes in cells.
- Specific inhibitor of SREBP activation.
- Impairs activation of SREBP-1 and SREBP-2.
- Inhibits ER-Golgi translocation of SREBPs.
- Decreases transcription of lipogenic genes.
- Exhibits antitumor properties.
- Lowers hyperglycemia in ob/ob mice.
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