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Medchemexpress LLC FAUC 213 | 337972-47-1 | 99.9% | C18H19ClN4 | 50 MG
SDP

Catalog No. 5000354753
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FAUC 213 is an orally active and highly selective dopamine D4 receptor complete antagonist with a Ki of 2.2 nM for hD4.4. It shows less activity on D2 and D3 receptors, with Kis of 3.4 μM and 5.3 μM respectively. This compound can cross the blood-brain barrier (BBB) and exhibits atypical antipsychotic characteristics.

  • Highly selective dopamine D4 receptor complete antagonist
  • Orally active
  • Crosses the blood-brain barrier (BBB)
  • Exhibits atypical antipsychotic characteristics
  • Inhibits p5-HT1 (Ki=1.2 μM), p5-HT2 (Ki=0.52 μM), and pα1 (Ki=0.27 μM)
  • Significantly reduces amphetamine-induced locomotor hyperactivity at 30 mg/kg
  • Restores prepulse inhibition reduction caused by apomorphine treatment at 30 mg/kg

Catalog No. 50-003-54753 Supplier Medchemexpress LLC Supplier No. HY1432750MG
May include imposed supplier surcharges.
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FAUC 213 is an orally active and highly selective dopamine D4 receptor complete antagonist with a Ki of 2.2 nM for hD4.4. It shows less activity on D2 and D3 receptors, with Kis of 3.4 μM and 5.3 μM respectively. This compound can cross the blood-brain barrier (BBB) and exhibits atypical antipsychotic characteristics.

  • Highly selective dopamine D4 receptor complete antagonist
  • Orally active
  • Crosses the blood-brain barrier (BBB)
  • Exhibits atypical antipsychotic characteristics
  • Inhibits p5-HT1 (Ki=1.2 μM), p5-HT2 (Ki=0.52 μM), and pα1 (Ki=0.27 μM)
  • Significantly reduces amphetamine-induced locomotor hyperactivity at 30 mg/kg
  • Restores prepulse inhibition reduction caused by apomorphine treatment at 30 mg/kg

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