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Medchemexpress LLC FB23 | 2243736-35-6 | 98.9% | 377.22 | 50 MG
SDP

Catalog No. 5000351292
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FB23 is a potent and selective FTO demethylase inhibitor with an IC50 of 60 nM. It directly binds to FTO and selectively inhibits FTO's mRNA N6-methyladenosine (m6A) demethylase activity.

  • Potent and selective FTO demethylase inhibitor
  • IC50 of 60 nM against FTO
  • Directly binds to FTO
  • Selectively inhibits FTO's mRNA N6-methyladenosine (m6A) demethylase activity
  • Inhibits proliferation of acute myeloid leukemia (AML) cells (e.g., NB4 and MONOMAC6)
  • Suppresses MYC and E2F targets
  • Activates apoptosis and p53 pathways

Catalog No. 50-003-51292 Supplier Medchemexpress LLC Supplier No. HY13718750MG
May include imposed supplier surcharges.
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FB23 is a potent and selective FTO demethylase inhibitor with an IC50 of 60 nM. It directly binds to FTO and selectively inhibits FTO's mRNA N6-methyladenosine (m6A) demethylase activity.

  • Potent and selective FTO demethylase inhibitor
  • IC50 of 60 nM against FTO
  • Directly binds to FTO
  • Selectively inhibits FTO's mRNA N6-methyladenosine (m6A) demethylase activity
  • Inhibits proliferation of acute myeloid leukemia (AML) cells (e.g., NB4 and MONOMAC6)
  • Suppresses MYC and E2F targets
  • Activates apoptosis and p53 pathways

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