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ACROBiosystems Biotinylated Human CD32a (H167R), His,Avitag (CDA-H82E5) is expressed from human 293 cells (HEK293). It contains AA Ala 36 - Ile 218 (Accession # NP_001129691.1).

Supplier:  ACROBiosystems CDAH82E525UG

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Receptors for the Fc region of IgG (Fc γ R) are members of the Ig superfamily that function in the activation or inhibition of immune responses. Three classes of human Fc γ Rs: RI (CD64), RII (CD32), and RIII (CD16), which generate multiple isoforms, are recognized. There are three genes for human Fcγ RII /CD32 (A, B, and C) and one for mouse Fcγ RII B (CD32B). CD32 is a low affinity receptor for IgG. The activating isoform, CD32A, is expressed on monocytes, neutrophils, platelets and dendritic cells. CD32A is expressed on many immune cell types (macrophage, neutrophil, eosinophils, platelets, dendritic cells and Langerhan cells), where inhibitory ITIM­bearing receptors may also be coexpressed and co­engaged by specific ligands.

Catalog No. 50-223-0930


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