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Medchemexpress LLC Fc gamma RIIB/CD32b 5ug | 5ug
Supplier: Medchemexpress LLC HYP768005UG
Fc RIIB/CD32b proteins exhibit low affinity as complexes or receptors that aggregate the immunoglobulin Fc region ITIM phosphorylated by Fc RIIB/CD32b recruits inositol phosphatases SHIP1 and SHIP2 inhibits Ras activation down-regulates MAPK activity reduces PLC- function and results in PKC activation Inhibition of MAP kinase pathway and anti-apoptotic kinase Akt inhibit cell proliferation and survival Fc gamma RIIB/CD32b Protein Cynomolgus (HEK293 His) is the recombinant cynomolgus-derived Fc gamma RIIB/CD32b protein expressed by HEK293 with C-His labeled tag
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