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AdipoGen Fc h IgG1 Ctrl recn-l
Supplier: AdipoGen AG35B0016C010
Recombinant Protein. Fc human IgG1 aa 100-330 containing 4 mutations. Source W2. Lyophilized. Contains PBS. Negative control in experiments with recombinant proteins fused to Fc human IgG1 non-lytic e.g. Prod. No. AG-40B-0230. This protein is not an appropriate negative control for other standard Fc protein constructs. Mutations to the complement C1q and FcgR I binding sites of the IgGs Fc fragment render the non-lytic proteins incapable of antibody-directed cytotoxicity ADCC and complement-directed cytotoxicity CDC.
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