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AdipoGen Fc hFasL Soluble hrec
Supplier: AdipoGen AG40B01323010
Protein. Human FasL aa 139-281 is fused at the N-terminus to the Fc portion of human IgG1. Source HEK 293 cells. Endotoxin content <0.01EU/µg purified protein LAL test Lonza. Lyophilized. Contains PBS. Binds to human and mouse Fas. Purity >95% SDS-PAGE. Fc humanFasL, Soluble human is a high activity construct in which two trimeric FasL are artificially linked via the Fc binding domain of human IgG1. This construct very effectively simulates the natural membrane-assisted aggregation of FasL in vivo. FasL is a cytokine that binds to TNFRSF6/Fas, a receptor that transduces the apoptotic signal into cells. It is involved in cytotoxic T cell mediated apoptosis and in T cell development.
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