AdipoGen Fc-KIH h IgG1 Ctrl rec

Supplier:  AdipoGen AG35B00153010

Recombinant Protein. Fc human IgG1 knobs-into-holes technology see reference J.B. Ridgway, et al. Protein Eng. 9, 617 1996. Source HEK 293 cells. Lyophilized. Contains PBS. Negative control in experiments with recombinant proteins fused to human IgG1 Fc-KIH Knobs-into-Holes e.g. Prod. No. AG-40B-0221. This protein is not an appropriate negative control for other standard Fc protein constructs. The protein Fc-KIH human IgG1 Control rec. is produced by using two different vectors, one encoding for the Fc Knobs sequence with a small linker synthesizing a protein of 29kDa and one encoding for the Fc Holes sequence synthesizing a protein of 28kDa. Both vectors transfected into HEK293 cells produce both Fc molecules Knobs-into-Holes technology J.B. Ridgway, et al. Protein Eng. 9, 617 1996 required for dimerization and for secretion of the final protein Fc-KIH human IgG1 Control rec..

Catalog No. 50-256-3075