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ACROBiosystems ACROBiosystems Human FcRn / FCGRT&B2M Heterodimer Protein, His Tag (SPR & BLI verified)
Supplier: ACROBiosystems FCNH52W750UG
Recombinant Protein;50UG;Human FCGRT&B2M Heterodimer Protein, His Tag (SPR & BLI verified) (FCN-H52W7) is expressed from human 293 cells (HEK293). It contains AA Ala 24 - Ser 297 (FCGRT) & Ile 21 - Met 119 (B2M) (Accession # P55899-1 (FCGRT) & P61769-1 (B2M)).;Human FCGRT&B2M Heterodimer Protein, His Tag (SPR & BLI verified), produced by co-expression of FCGRT and B2M, has a calculated MW of 32.3 kDa (FCGRT) and 11.7 kDa (B2M). Subunit FCGRT is fused with a polyhistidine tag at the C-terminus and subunit Beta-2 microglobulin (B2M) contains no tag at the C-terminus. The reducing (R) protein migrates as 33 kDa (FCGRT) and 10 kDa (B2M) respectively due to glycosylation.;Captured Human FCGRT&B2M Heterodimer Protein, His Tag (SPR & BLI verified) (Cat. No. FCN-H52W7) on CM5 Chip via Anti-His antibody can bind Herceptin (Trastuzumab) with an affinity constant of 0.516 μM as determined in a SPR assay (Biacore T200) (QC tested).
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