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Medchemexpress LLC FD-IN-1 | 1646682-14-5 | 98.6% | 100 MG
Supplier: Medchemexpress LLC HY128570100MG
FD-IN-1 (Compound 12) is an orally bioavailable and selective factor D (FD) inhibitor with an IC50 of 12 nM. Complement FD, a highly specific S1 serine protease, plays a central role in the alternative complement pathway of the innate immune system. FD-IN-1 also inhibits factor XIa (FXIa) and Tryptase β2 with IC50s of 7.7 μM and 6.5 μM, respectively. It appears as a white to off-white solid.
- Selective factor D inhibition
- Orally bioavailable
- Systemic and local suppression of AP activation
- Research use
- Potential for autoimmune and inflammatory diseases
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