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Medchemexpress LLC FD-IN-1 | 1646682-14-5 | 98.6% | 50 MG
Supplier: Medchemexpress LLC HY12857050MG
FD-IN-1 is an orally bioavailable and selective factor D (FD) inhibitor with an IC50 of 12 nM, central to the alternative complement pathway of the innate immune system. It also inhibits factor XIa (FXIa) and Tryptase β2 with IC50s of 7.7 and 6.5 μM, respectively. This compound demonstrates systemic suppression of AP activation in vivo and high oral bioavailability in mice (83%) and dogs (70%).
- Orally bioavailable and selective factor D inhibitor
- Inhibits factor XIa and Tryptase β2
- Systemic suppression of AP activation in vivo
- High oral bioavailability
- Suitable for research use only
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