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Selleck Chemical LLC Fedratinib (TG101348) 5mg 936091-26-8 SAR302503
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Supplier:  Selleck Chemical LLC S27365MG

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Fedratinib (SAR302503, TG101348) is a selective inhibitor of JAK2 with IC50 of 3 nM in cell-free assays, 35- and 334-fold more selective for JAK2 versus JAK1 and JAK3. Fedratinib also inhibits FMS-like tyrosine kinase 3 (FLT3) and RET (c-RET) with IC50 of 15 nM and 48 nM, respectively. Fedratinib has potential antineoplastic activity. Fedratinib inhibits proliferation and induces apoptosis. Phase 2. *For Research & Development use only.  Product is not intended for drug, household, or human consumption.

Catalog No. 50-194-7954


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