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Medchemexpress LLC Fedratinib hydrochloride hydrate | 1374744-69-0 | 99.9% | 615.62 | 500 MG
Supplier: Medchemexpress LLC 500MGHY10409A
Fedratinib hydrochloride hydrate is a potent, selective, ATP-competitive, and orally active JAK2 inhibitor. It has IC50s of 3 nM for both JAK2 and JAK2V617F kinase. This compound exhibits 35-fold selectivity over JAK1 and 334-fold selectivity over JAK3. It induces cancer cell apoptosis and is being researched for its potential in treating myeloproliferative disorders.
- Potent, selective, ATP-competitive, and orally active JAK2 inhibitor
- Induces cancer cell apoptosis
- Potential for myeloproliferative disorders research
- Shows selectivity over JAK1 and JAK3
- Available in various quantities for research use
- Comes with data sheet, COA, SDS, and handling instructions
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