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Apexbio Technology LLC Fenbendazole 43210-67-9 10mM (in 1mL DMSO)
Supplier: Apexbio Technology LLC A26105.1
Fenbendazole (CAS 43210-67-9) is a small-molecule inhibitor targeting microtubule polymerization It is designed to bind tubulin and disrupt microtubule dynamics thereby impairing cytoskeletal integrity and protein homeostasis Fenbendazole exerts its biological activity primarily through microtubule destabilization and disruption of proteasomal function triggering the unfolded protein response (UPR) pathway In various cancer cell lines fenbendazole demonstrates cytotoxic and anti-proliferative activity with reported IC50 values generally ranging from approximately 0 5 to 5 M Based on these pharmacological properties fenbendazole holds research potential in antiparasitic therapy and cancer drug repurposing studies
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