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Medchemexpress LLC Fenbendazole-d3 | 1228182-47-5 | 99.70% | 5 MG
Supplier: Medchemexpress LLC HYB0413S5MG
Fenbendazole-d3 is a deuterium-labeled version of Fenbendazole. It acts as a HIF-1α agonist, stimulating the HIF-1α-related GLUT1 pathway. Fenbendazole is an orally active benzimidazole anthelmintic agent known for its broad antiparasitic effects. It functions as a microtubule destabilizing agent, leading to cell-cycle arrest and mitotic cell death, and has also demonstrated antitumor activity in mice xenografted with wild-type p53.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Reverses the inhibiting influence exerted by miR-143-5p on proliferation, colony-forming capacity, and migration in BT-549 and MCF-7 cells at 20 μM for 48 h
- Elevates the protein expression levels of HIF-1α and GLUT1 in BT-549 and MCF-7 cells at 10 μM for 48 h
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