Medchemexpress LLC Fendiline (hydrochloride) | 13636-18-5 | 99.8% | 1 ML

Supplier:  Medchemexpress LLC HYB098410MM/1ML

Fendiline hydrochloride is a diphenylalkylamine type of antianginal agent that acts as an L-type calcium channel blocker with an IC50 of 17 μM. It is also identified as a selective K-Ras inhibitor, showing no effect on H-Ras and N-Ras. It inhibits K-Ras plasma membrane localization (IC50 of 9.64 μM) and K-Ras signal output. Additionally, Fendiline hydrochloride is a STING agonist and has demonstrated the ability to inhibit the growth of multiple refractory cold tumors. This product is provided as a 10 mM solution in 1 mL of DMSO with a purity of 99.78%.

• Acts as an L-type calcium channel blocker
• Functions as a selective K-Ras inhibitor
• Inhibits K-Ras plasma membrane localization
• Suppresses K-Ras signal output
• Prevents proliferation of various cancer cell lines
• Serves as a STING agonist
• Inhibits growth of refractory cold tumors

Catalog No. 50-004-08971