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Cayman Chemical FerrItIn PROTAC DeFer-2 5mg
Supplier: Cayman Chemical 389315 MG
A PROTAC that drives ferritin degradation; induces ferritin degradation in B16/F10 cells at 0.5 µM; increases intracellular levels of free iron and induces pyroptosis in B16/F10 cells at 5 µM; ferritin PROTAC DeFer-2 encapsulated in albumin nanoparticles reduces tumor growth and increases survival in a B16/F10 murine melanoma model at 10 mg/kg
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