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Enzo Life Sciences Ferutinin (high purity) (5mg). CAS: 41743-44-6
Supplier: Enzo Life Sciences ALX350098M005
Potent, naturally occuring non-steroid estrogenic compound. Agonist for estrogen receptor (ER) α and agonist/antagonist for ERβ with higher binding affinity than tamoxifen (ALX-550-095) for both ERs. Electrogenic Ca2+ ionophore inducing mitochondrial depolarisation which can be completely blocked by cyclosporin A (BML-A195), suggesting that ferutinin opens the mitochondrial permeability transition pore (mPTP). In a concentration range of 1-50µM ferutinin increases the permeability of thymocytes, mitochondria, sarcoplasmic reticulum, liposomes and bilayer lipid membranes for Ca2+. Purity: ≥98% (HPLC). Appearance: White to off-white solid. Solubility: Soluble in acetone, dichloromethane, DMSO or ethyl acetate. Long Term Storage: +4°C.
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