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Medchemexpress LLC Fexofenadine | 83799-24-0 | >99.8% | 50 MG
Supplier: Medchemexpress LLC HYB080150MG
Fexofenadine (MDL-16455) is an orally active and nonsedative H1 receptor antagonist. It is used in allergic rhinitis and chronic idiopathic urticarial research. Fexofenadine inhibits the expression of IL-6 protein in nasal fibroblasts in a dose-dependent manner and blocks phosphorylated p38 activation in histamine-induced nasal fibroblasts. In animal models, Fexofenadine hydrochloride has been shown to suppress both eosinophilia and systemic anaphylaxis in mice infected with *T. spiralis*.
- Orally active and nonsedative H1 receptor antagonist.
- Useful in allergic rhinitis and chronic idiopathic urticarial research.
- Inhibits IL-6 protein expression in nasal fibroblasts.
- Blocks phosphorylated p38 activation in histamine-induced nasal fibroblasts.
- Suppresses eosinophilia and systemic anaphylaxis in animal models.
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