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Cayman Chemical FexofenadInhydrochlorIde 100mg

Supplier: Cayman Chemical 18191100 MG

An irreversible inhibitor of mutant forms of EGFR including T790M (Ki 21.5 nM) with minimal activity at the wild-type EGFR (Ki 303.3 nM) inhibits the proliferation of NSCLC cells expressing mutant EGFR (GI50s 7-32 nM) and demonstrates anti-tumor activity in NSCLC EGFR mutant xenograft and transgenic models
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