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Cayman Chemical FezolIntnt 50mg
Supplier: Cayman Chemical 3952350 MG
An NK3 receptor antagonist (IC50 = 20 nM); decreases plasma levels of LH in castrated cynomolgus monkeys at 5 mg/kg; prevents increases in body weight and food intake but does not affect uterine weight or plasma levels of estradiol, FSH, progesterone, or testosterone in ovariectomized rats at 10 mg/kg; inhibits increases in skin temperature but not core temperature, indicating regulation of hot flash-like symptoms, in ovariectomized rats at 3 or 10 mg/kg
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