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Cayman Chemical FFA asy Sample Buffer 1ea

Supplier: Cayman Chemical 7003171 EA
A PROTAC that drives Cdk2 degradation selectively degrades Cdk2 (IC50 24 nM) over seven additional CDKs at 500 nM but also degrades Aurora A kinase and IKZF1 at 250 nM reduces Cdk2 levels and increases the percentage of cells expressing CD11b a marker of differentiation in primary AML cells decreases proliferation without reducing the viability of as well as induces differentiation in primary HSCs
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