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Abcam FFN511, Fluorescent substrate for VMAT2, 5MG

Supplier:  Abcam AB1203315MG

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MW 284.35 Da, Purity >98%. First novel fluorescent false neurotransmitter. Enables optical imaging of presynaptic terminal activity. Inhibits 5-HT binding to VMAT2 (IC₅₀ = 1 μM (comparable to dopamine itself)). Released via exocytosis in the striatum in mouse acute slice preparation. Labels dopamine and other presynaptic terminals in the striatum. Compatible with GFP tags and other optical probes. Sufficiently bright, photostable and suitable for two-photon fluorescence microscopy. View the technique online For highly selective labelling of dopaminergic presynaptic termainals FFN102 (ab120866) is recommended.

The product is subject to the following: Abcam Restricted Use Statement

Catalog No. 50-270-7669


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