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Apexbio Technology LLC FG-4592 (ASP1517) 808118-40-3 10mM (in 1mL DMSO)
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Supplier:  Apexbio Technology LLC A41875.1

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FG-4592 (ASP1517 CAS 808118-40-3) is a small molecule inhibitor of hypoxia-inducible factor prolyl hydroxylase (HIF-PH) an enzyme responsible for regulating endogenous erythropoietin (EPO) expression Inhibition of HIF-PH by FG-4592 results in stabilization and accumulation of hypoxia-inducible factor (HIF) thereby promoting EPO synthesis and stimulating erythropoiesis Clinical research is ongoing to investigate oral FG-4592 as a treatment for anemia associated with chronic kidney disease (CKD) particularly focusing on patients both dependent and independent of dialysis

Catalog No. 50-000-61449


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