Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
AdipoGen FGF-23 mouseFc h rec
Supplier: AdipoGen AG40A0128YC010
Recombinant protein. Mouse FGF-23 aa25-251 is fused at the C-terminus to the Fc portion of human IgG1. Activates ERK and FRS2alpha phosphorylation in Klotho expressing cells. Source/Host HEK 293 cells. Purity >90% SDS-PAGE. Lyophilized. Contains PBS. FGF-23 Fibroblast growth factor 23 is a regulator of phosphate homeostasis. It upregulates EGR1 expression in the presence of KLBy. Acts directly on the parathyroid to decrease PTH secretion. Regulates the vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization. Defects in FGF-23 are the cause of autosomal dominant hypophosphataemic rickets ADHR and of hyperphosphatemic familial tumoral calcinosis HFTC.
Product Content Correction
The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction